Ipepile eshushu (i-capsaicin) itshisa ezandleni, esikhumbeni nasemehlweni¶

Ukusika ijalapeno ekrwada, i-habanero, i-Scotch bonnet, iliso lentaka, okanye iindidi ezishushu kakhulu ze-Capsicum chinense (ezifana nepepile yesiporho, oonomadudwane baseTrinidad Moruga, okanye iCarolina Reapers) ngaphandle kweeglavu ze-nitrile zihlala zixhokonxa imvakalelo etshisayo, yeeyure ezinde zeneurogenic, ubuso, iminwe, iinzipho okanye iinzipho. Ngokwekliniki eyaziwa ngokuba yi Hunan hand syndrome (contact capsaicin dermatitis), le ntlungu ingamandla ivakala ifana neqondo lesibini lokutshisa okushushu okanye ukutshisa kwamanzi abilayo, kodwa ulusu alufane lube namadyunguza okanye lube necrosis yeselula.

Ngenxa yokuba i-capsaicin (i-$ 8\text{-methyl-}N\text{-vanillyl-}6\text{-nonenamide}$) i-hydrophobic, ioli ye-resinous non-polar (oleoresin capsicum), amanzi alula awayinyibilikisi. Ukubaleka amanzi etephu abandayo phezu kwezandla eziqatywe ipepile okanye ukuhlanjululwa komlomo ovuthayo ngamanzi ngokulula nje kusasaza amathontsi e-oyile encinci kwindawo ebanzi yolusu kunye nenwebu. Uncedo luxhomekeke ekuqondeni indlela i-capsaicin evala ngayo kwii-receptors zentlungu kunye nokusebenzisa i-solvents yamachiza afanelekileyo, i-surfactants, okanye iiprotheni zobisi ukuhluba iimolekyuli ze-lipid ngaphandle kwesikhumba ngokukhuselekileyo.

Yenza oku ngoku¶

1. Biza iinkonzo ezingxamisekileyo ukuba ukudumba okumandla komzila womoya okanye ukuvuthuza kwesifuba kuyaqala: Ngelixa i-capsaicin ibangela iintlungu ze-neurogenic endaweni yokutshisa okwenyani, ukuphefumla i-aerosolized super-hot pepper steam okanye ipepile yokutshiza kunokuxhokonxa ubomi be-bronchospasm okanye i-anaphylaxis; fowunela inombolo yakho yexesha likaxakeka (911 eUnited States naseKhanada, 112 kulo lonke elaseEuropean Union, 999 eUnited Kingdom, okanye ubone amanani kaxakeka directory) ukuba ukuphefumla kuba nzima.
2. **Ungaze usebenzise amanzi alula wedwa eluswini, kwaye ungaze uhlikihle amehlo okanye igroin **: Amanzi angenanto agxotha i-capsaicin esekwe kwi-oyile kwaye ayisasaze eluswini olungachaphazelekiyo; gcina iminwe engcolisekileyo ikude ngokungqongqo emehlweni akho, impumlo, imilebe, kunye neendawo zoqhagamshelwano lokuhlambela.
3. Izandla kunye nolusu, hlikihla ngokucokisekileyo nge-oyile yemifuno okanye isepha yokusika igrisi kuqala: Gcoba izandla ezivuthayo kwi-oyile yemifuno elulwelo, i-oyile ye-olive, okanye uhlikihle utywala imizuzwana engama-60 ukunyibilikisa i-lipid resin, emva koko ukhuhle ngesicoci sesitya esisikwa igrisi (esifana neDawn okanye i-Fairy tonsemuls kunye ne-Fairy tonsemuls).
4. Amehlo, susa iilensi zokudibana ngokukhawuleza kwaye ugungxule imizuzu eyi-15 nge-saline eyinyumba okanye amanzi apholileyo: Ngokungafaniyo nesikhumba esipheleleyo, i-cornea ayikwazi ukunyamezela iisepha, i-oyile, okanye utywala; bamba iinkophe zivuleke kwaye unkcenkceshele ngokuqhubekayo ukusuka kwikona engaphakathi ukuya ngaphandle usebenzisa ukuhlamba kwamehlo okungenazintsholongwane okanye umlambo othambileyo wamanzi etephu apholileyo.
5. cwina iminwe ebuhlungu kubisi olubandayo okanye iyogathi enamafutha agcweleyo: Emva kokuhlamba i-oyile engaphezulu ngesepha yesitya, ntywilisela iminwe eshukumayo kwisitya sobisi olubandayo olupheleleyo okanye uyiqabe ngeyogathi yeGreek enamafutha; iprotein yobisi i-lipophilic casein isebenza njengemolekyuli yesicoci esitsala i-capsaicin kwiisiphelo zemithambo-luvo.
6. Coca phantsi kweminwe yakho ngentlama yesoda yokubhaka, isepha yesitya, kunye neoyile: Ioyile yeCapsaicin izimela ngaphantsi kwencam yeenzipho (hyponychium) ukuya kutsho kwiiyure ezingama-24; sebenza ngobunono intlama ye-oyile-nesepha phantsi kwezikhonkwane usebenzisa ibhrashi yamazinyo ethambileyo ukuze ungawatshisi kwakhona amehlo akho ngosuku olulandelayo.

I-biochemistry ye-capsaicin: kutheni ivakalelwa njengomlilo ngaphandle kwezicubu ezivuthayo¶

Ukunyanga itshilisi ipepile ngokutshisa ngempumelelo, kuyanceda ukuqonda ukuba kutheni ingqondo yakho ibona ioyile ekrwada yetshilisi njengomlilo wokoqobo kwaye kutheni amayeza aqhelekileyo okutshisa engaphumeleli.

I-Scoville Heat Units (SHU) kunye nobunzulu bokungena kwesikhumba¶

Ubunzima kunye nobude be-Hunan Hand Syndrome Scale ngokuthe ngqo kunye noxinaniso lwe-capsaicinoids (i-capsaicin kunye ne-dihydrocapsaicin) ngaphakathi kweembambo ze-placenta zangaphakathi zepepile (i-pith emhlophe apho imbewu inamathele khona, ebamba ukuya kumaxesha ali-16 ngaphezulu kwe-capsaicin kunodonga lwenyama yangaphandle):

• IPeppers yeCulinary ephakathi ukuya kwephakathi (1,000 ukuya ku-50,000 SHU): I-Jalapeño, iFresno, i-serrano, i-cayenne, kunye netshilisi yamehlo entaka yaseThai zibangela ukutshisa komphezulu kwiincam zeminwe kunye neecuticles ezifikelela incopho kwimizuzu engama-30 kwaye isombulule ngaphezulu kweeyure ezi-2 ukuya kwezi-6 emva kokuhlanjwa kwe-solvent.
• IiPeppers zeCulinary ezishushu ezongezelelweyo (100,000 ukuya kwi-350,000 SHU): IHabanero, i-Scotch bonnet, i-fatalii, kunye nepepile ye-datil zingena ngokukhawuleza kwi-lipid matrix ye-outer stratum corneum (ingakumbi ukuba izandla zichathiwe okanye zithanjiswe yintlungu enzulu ye-8 yekhitshi),
• ** I-Super-Hot Peppers kunye ne-Oleoresin Extracts (800,000 ukuya kwi-16,000,000 SHU)**: I-pepper yesiporho (Bhut Jolokia), i-7-Pot, i-Trinidad Scorpion, i-Carolina Reaper, kunye ne-concentrated pepper extracts zingena nzulu kwi-dermal papillae kunye neebhedi zezikhonkwane. Ukudibana kwesikhumba okungahlanjwanga kunokubangela i-edema yendawo enzima, i-tachycardia enovelwano, isicaphucaphu, kunye nokutshisa okungapheliyo kwe-neuropathic okuthatha iiyure ezingama-24 ukuya kwezingama-48.

flowchart TD
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Iprotocol yenyathelo ngenyathelo "yesandla sikaHunan" kunye nokutsha kwesikhumba¶

Xa iminwe yakho, iintendelezo, izibonda, okanye ubuso buqala ukutshisa emva kokusika i-chilies, isepha elula kunye namanzi ahlala ehluleka ngenxa yokuba i-capsaicin sele ihlukaniswe kwi-sebum yendalo kunye ne-lipid bilayers yesikhumba sakho. Kufuneka usebenzise inqanaba ezibini le-lipophilic extraction method: okokuqala ukunyibilikisa i-resin kwi-oyile engamanzi okanye kwisinyibilikisi se-alcohol, kwaye emva koko ukhuphe umxube we-oyile-capsaicin kunye ne-surfactant eyomeleleyo.

Inqanaba loku-1: Nyibilikisa i-resin engeyo-polar (Khetha isinyibilikisi esinye)¶

Phambi kokuba uvule itephu yamanzi, sebenzisa isinyibilikisi esinye kwezi zilandelayo ngqo kwizandla zakho ezomileyo okanye ezifumileyo kwaye uziphulule ngokucokisekileyo kuzo zonke iintende, phakathi kweminwe, phezu kwamaqupha, nangaphantsi kweenzipho isithuba esipheleleyo ama-60 ukuya kwimizuzwana engama-90:

1. I-Liquid Vegetable Oil, Olive Oil, Canola Oil, or Coconut Oil (Eyona nto ingcono kwisikhumba esiqinileyo okanye esikrazukileyo): Galela amacephe a-1 ukuya kwi-2 (i-15 ukuya kwi-30 milliliters) ye-oyile yokupheka yasekhitshini ezandleni zakho. Njengokunyibilika okunje: iimolekyuli ze-non-polar triglyceride kwibhondi yeoli yokupheka kunye nomsila we-hydrophobic hydrocarbon yeemolekyuli ze-capsaicin, ukukhupha ioli yepepile kwimibhobho yolusu lwakho kwaye uyimise ngaphakathi kwioyile yokupheka engamanzi.
2. Isopropyl Alcohol (70% Rubbing Alcohol) okanye High-Proof Vodka/Ethanol (Esona sinyibilikisi esikhawulezayo somphezulu, thintela kumanxeba avulekileyo): ICapsaicin inyibilika ngokungaqhelekanga etywaleni. Ukugalela i-alcohol yotywala okanye i-high-proof spirit phezu kwezandla ezingaguqukiyo kunyibilikisa i-capsaicin ephezulu kwimizuzwana. Sula utywala kunye nethawula yephepha kunokuba uvumele ukuba uphuphe endaweni, kuba ukuba utywala buphuphuma nje ezandleni zakho, bushiya idiphozithi ye-capsaicin echithiweyo emva kwesikhumba sakho.
3. Ibhotolo yamandongomane eFat kakhulu okanye iJeli yePetroleum: Ukuba ioli yolwelo yokupheka ayikho, ukuhlikihla umaleko oshinyeneyo webhotolo yamandongomane, ibhotolo, unciphiso, okanye iVaseline kuzo zonke izandla kusebenza ngendlela efanayo yokwahlula-hlula ilipid.

Inqanaba lesi-2: Emulsify kwaye uhlube ngesicoci sokusika igrisi¶

Nje ukuba i-capsaicin inyibilike ngaphakathi kwinqanaba leoli yokupheka ezandleni zakho, kufuneka uyisuse ngokupheleleyo ioli:

1. Ngaphandle kokuhlamba kuqala, squirt isixa esikhulu se- **egxininisiweyo sesepha yolwelo yokusika igrisi yolwelo lokuhlamba izitya ** (hayi isepha yesandla ethambisayo ethambileyo) ngqo kwizandla zakho eziqatywe ioyile.
2. Hlikihla izandla zakho ngamandla imizuzwana engama-45 ukuze i-micelles ye-surfactant igqume i-oyile yokupheka ene-capsaicin.
3. Sebenzisa ibhrashi ethambileyo yebristle okanye ikona yelaphu lokuhlambela ukukhuhla ngobunono phantsi kweenzipho kunye nokujikeleze iicuticles.
4. Hlamba ngocoselelo phantsi kwe-amanzi apholileyo ahamba empompo (angaze ashushu okanye ashushu amanzi, avula imingxunya yolusu kwaye ivule intshukumo TRPV1 ii-receptors zobushushu).
5. ** Phinda umjikelo we-oyile-ke-dish-sepha amaxesha angama-2 ukuya kwe-3 ** de kube konke ukutyibilika komphezulu kuphelile.

Inqanaba lesi-3: Ukunciphisa iintlungu zemithambo-luvo emva kokuhlanjwa¶

Ukuba ugawule ipepile kangangemizuzu engama-20 phambi kokuba uve ukutsha, ezinye iimolekyuli ze-capsaicin sele zifudukile ngaphaya koqweqwe olungaphandle lwesikhumba esifileyo (i-stratum corneum) ukuya kutsho kwiziphelo zemithambo-luvo apho isepha ingenakufikelela khona. Emva kokuba i-oyile engaphezulu ihlanjiwe, sebenzisa ezi ndlela zijoliswe kuzo ukuzolalisa ukudubula TRPV1 abamkeli:

• I-Cold Casein Dairy Soak: Galela ubisi lwenkomo olubandayo lomkhenkce, isiqingatha nesiqingatha, okanye ulwelo lokutshayela ikhrimu kwisitya esincinci (okanye usasaze umaleko oshinyeneyo weyogathi yeGreek enamafutha agcweleyo okanye ukhilimu omuncu ezandleni zakho). I-Casein yi-phosphoprotein ejikeleze iiglobhu zamafutha ebisi; ibophelela ngokuqinileyo kwiimolekyuli ze-capsaicin eziseleyo kwimibhobho yolusu ephezulu ngelixa ubushushu obubandayo butyhala ubushushu bolusu ngaphantsi kwe-30-degree-Celsius. TRPV1 ukudubula umda.
• Kutheni kufuneka uthathe ikhefu lomjikelo kumanzi omkhenkce: Ukubamba izandla zakho emanzini omkhenkce okanye ubisi olubandayo kuthintela ukutshisa ngokukhawuleza kuba ukupholisa ulusu ngaphantsi kwe-25 degrees Celsius (77 degrees Fahrenheit) kuvala umzimba TRPV1 isango le-ion channel. Nangona kunjalo, oko nje ukhupha izandla zakho kwisitya esibandayo kwaye umzimba wakho ufudumeza ulusu ubuyele ngaphezulu kwe-30 degrees celsius, iintlungu ziyagquma. **Ungaze ucwilise izandla zakho ngokuqhubekayo emanzini omkhenkce okanye ubambe iityhubhu ze-ice ezingenanto ngaphezu kwemizuzu eyi-10 ngexesha **, okanye unokubangela i-vasoconstriction ebangelwa ukubanda kunye ne-frostnip (ukulimala okubandayo okungenakuqhaqha). Gxila imizuzu eyi-10, susa kwaye uyomise imizuzu eyi-10 phambi kwefeni yombane epholileyo, kwaye uphinde.
• Topical Lidocaine (4% Over-the-Counter Anesthetic Cream or Gel): Emva kokuba izandla zakho zihlanjwe ngokupheleleyo ngaphandle kwe-oyile yomhlaba kwaye zomisiwe, usebenzisa i-over-the-counter ** i-4 pesenti ye-lidocaine yokutshisa i-gel okanye i-cream ** iibhloko ze-voltage-gated iziteshi ze-sodium ecaleni kwe-C-fiber nerves, ukumisa umqondiso weentlungu ekuhambeni ukuya kwintambo yomgogodla. (Qaphela: I-topical hydrocortisone steroid cream inefuthe elincinane kakhulu elikhawulezileyo kwiintlungu ezibukhali ze-capsaicin kuba iintlungu ziqhutywa kukusebenza ngokuthe ngqo kwe-ion-channel kune-histamine okanye ukudumba kwamajoni omzimba.)

Iprothokholi engxamisekileyo yepepile yechili okanye i-capsaicin emehlweni¶

Ukuchukumisa iliso lakho ngengozi emva kokuphatha iipepile ezishushu, okanye ukuvezwa kwi-aerosolized chilisi inkungu okanye i-oleoresin capsicum (OC) yokuzikhusela isitshizi, kubangela ukuqaqamba kwenkophe ekhawulezileyo (blepharospasm), ukukrazuka okukhulu, ububomvu beconjunctival, kunye neentlungu ezitshisayo.

1. Susa iilensi zoqhagamshelwano ngoko nangoko¶

Ukuba unxibe iilensi zokudibanisa, hlamba izandla zakho ngokukhawuleza ngesepha yesitya (okanye unomncedisi ongangcolisekanga ukuncedise) kwaye ukhuphe iilensi emehlweni akho kwangoko.

• Lahla i-hydrogel ethambileyo okanye i-silicone-hydrogel contact lens: Iilensi zoqhagamshelwano ezithambileyo ziziponji ezinepolymer ezifunxa ioyile ye-hydrophobic capsaicin nzulu kwimatrix yazo. Akukho sisombululo sokucoca i-lens yasekhaya sinokususa i-capsaicin efunthiweyo kwi-lens ethambileyo; ukubuyisela le lensi kwiliso lakho kwiintsuku kamva kuya kutshisa i-cornea yakho kwakhona. Lahla iilensi ezithambileyo ezingcolisekileyo kwinkunkuma.
• Iilensi zerhasi eziqinileyo (RGP): Iilensi eziqinileyo zinokucocwa ngobungcali ngezicoci zelensi ezikhethekileyo ngugqirha wamehlo, nangona ukucocwa okucokisekileyo kwesepha kunye netyuwa kuyafuneka phambi kokuba ziphinde zisetyenziswe.

2. nkcenkceshela nge-saline engenazintsholongwane okanye ngamanzi abalekayo apholileyo kangangemizuzu eyi-15¶

Nangona amanzi enganyibiliki i-capsaicin ngokwekhemikhali, **i-high-volume mechanical flushing ** ngumgangatho wokunyamekela kwamehlo kuba i-cornea ayikwazi ukunyamezela i-lipid solvents okanye i-detergents enzima. Jonga izikhokelo zethu ukwenzakala kwamehlo kwaye ukutshisa kakhulu kunye nokugungxulwa kweekhemikhali ukuseta ukunkcenkceshela:

1. Yayama phezu kwe sinki okanye ungene kwishawari epholileyo. Nyakazisa intloko yakho emacaleni ukuze iliso elichaphazelekayo libe ngaphantsi kuneliso elingachaphazelekiyo (ukuthintela amanzi abalekayo ekuhlambeni ioli yetshili kwibhulorho yempumlo kwiliso lakho elilungileyo).
2. Ngenxa yokuba i-capsaicin ibangela ukuncwina okukhulu okungafunekiyo (i-blepharospasm), sebenzisa ubhontsi wakho kunye nomnwe wesalathisi (ogqunywe ngethishu ecocekileyo eyomileyo ukuba iminwe yakho isenayo i-oyile yetshili kuyo) ukuze ** ubambe zombini iinkophe zivuleke kakhulu **.
3. Galela i-isotonic ecocekileyo yamehlo enetyuwa, ulwelo lwesikhululo samehlo sorhwebo, okanye umjelo woxinzelelo oluphantsi wamanzi etephu apholileyo kwibhulorho yempumlo ukuze aqukuqelele ngokuthe chu kwibhola yeliso ukusuka kwikona engaphakathi (i-canthus ephakathi) ngaphandle kwetempile engaphandle kangangemizuzu eyi-15* epheleleyo.
4. Qeqesha iliso lakho liye phezulu, ezantsi, ekhohlo, nasekunene ngokuqhubekayo ngexesha lokugungxula ukuze amanzi ahlanjululwe aphume amantla nasezantsi eenkophe (iipokotho ezinzulu emva kweenkophe).

3. Hlamba iinkophe kunye namashiya ngeShampoo yomntwana engenazinyembezi¶

Emva kokuba unkcenkceshelwe i-eyeball evulekileyo imizuzu eyi-15 ngamanzi okanye i-saline, amathontsi e-microscopic yeoli ye-capsaicin ahlala ebambelele kwi-eyelashes enamafutha kunye nemida ye-eyelid, ehlamba kwakhona esweni rhoqo xa uqhwanyaza.

• Vala amehlo akho ngobunono (musa ukuwakhama uwavale ngokuqinileyo).
• Beka ithontsi elincinci leshampu yomntwana engakrazuli zinyembezi** (okanye isicoci senkophe esinegwebu esikhethekileyo) kwiphedi yomqhaphu ecocekileyo okanye ilaphu lokuhlamba elicocekileyo.
• Sula ngobunono kwi-eyelashes evaliweyo kunye namashiya ukuze wenze i-oyile eseleyo kwi-shafts yeenwele, emva koko uhlambulule kakuhle ngamanzi apholileyo eminye imizuzu emi-2 ngaphambi kokuba uvule amehlo akho.
• Hlala phambi kwefeni epholileyo kwaye uqhwanyaze ngokukhawuleza; umoya ovulekileyo wokukrazula umphunga upholisa umphezulu we-cornea kwaye ukhawuleze ukuchacha.

4. Iiflegi ezibomvu ezifuna uvandlakanyo olungxamisekileyo lwe-ophthalmology¶

Funa ukhathalelo lwezonyango olukhawulezileyo kwisebe likaxakeka okanye ugqirha wamehlo/ugqirha wamehlo kwiklinikhi ukuba kukho naziphi na ezi mpawu zilandelayo ziyaqhubeka ** ngaphezu kweeyure ezi-2 emva kokugqiba ukunkcenkceshela**:

• Ukubona luzizi okuthe gqolo, iihalos ezijikeleze izibane, okanye ukuncipha kokubona kakuhle.
• Uvakalelo lokuba isuntswana elibukhali eliqinileyo likrwempa i-cornea ngalo lonke ixesha uqhwanyaza (elinokubonisa iqhekeza lembewu yetshilisi egciniweyo phantsi kwejwabu le-epithelial elingaphezulu okanye i-corneal epithelial abrasion ebangelwa kukuhlikihla amehlo akho ngexesha loloyiko lokuqala).
• I-Purulent (etyheli okanye eluhlaza) ukukhutshwa kwamehlo okanye ukudumba okumandundu ngosuku olulandelayo.

Ukunciphisa i-groin ngengozi, i-mucosal, okanye ukutshisa ubuso¶

Ukuya kwindlu yangasese ngaphambi kokuba uqonde ukuba izandla zakho ziqatywe kwi-jalapeño okanye i-oyile ye-habanero yenye yezona meko zingxamisekileyo nezibuhlungu ekhitshini ngenxa yokuba izicubu ze-mucosal ziswele umaleko ongqindilili okhuselayo wekeratin.

1. Musa ukukhuhla umuco obuthathaka ngotywala, iblitshi, okanye isepha yesitya erhabaxa: Ungaze usebenzise isicoci sokuthambisa esinxilisayo, iacetone, okanye isicoci sesitya esigxininisiweyo kwilungu lobufazi, kwiimpumlo, okanye emilebeni, njengoko ezi zinyibilikisi zibangela ukucaphuka okwesibini kwekhemikhali kwiinwebu ezibhityileyo zamafinyila.
2. Faka icompress yobisi ebandayo kwangoko: Gxisa ilaphu lokuhlamba elicocekileyo kubisi olubandayo lomkhenkce okanye usasaze umaleko oshinyeneyo weyogathi enamafutha apheleleyo ebandayo, ecacileyo, engenaswekile okanye ukhilimu omuncu ngokuthe ngqo kwindawo echaphazelekayo ye-mucosal okanye yobuso. Yiyeke kwindawo yemizuzu emi-5 ukuya kweli-10 ukuze amanqatha obisi kunye ne-casin zifunxe umphezulu we-capsaicin ngelixa ubushushu obubandayo buyayeka. TRPV1 ukudubula.
3. Yenza ukucocwa kwe-oyile ethambileyo: Sula ngobunono indawo ngephedi yomqhaphu efakwe kwi-oyile yomnquma esulungekileyo, i-oyile yekhokhonathi, okanye i-mineral baby oil ukunyibilikisa i-capsaicin eseleyo, emva koko uhlambe ngobunono kwishawari epholileyo usebenzisa ulwelo oluthambileyo lokuhlamba okanye ishampu yosana.

Ukunciphisa ukutshisa komlomo, umlomo, kunye nomqala emva kokutya iipepile ezishushu kakhulu¶

Xa usitya i-pepper eshushu ngokungalindelekanga okanye i-sauce eshushu ibangela umlomo obuhlungu, ulwimi, kunye nokutshisa kwe-esophageal:

• Indlela yobisi lweSwish-and-Tpit: Thatha ubisi olubandayo olupheleleyo emlonyeni, ukhilimu omuncu, okanye i-ayisikhrimu enyibilikisiweyo. Yijike ngamandla ujikeleze ulwimi lwakho, iintsini, kunye nezidlele imizuzwana engama-20 ukuya kwengama-30 ukuze i-casein kunye namafutha obisi athathe ioyile ye-capsaicin yasimahla, kwaye ** uyitshice kwi-sink ** kunokuba uginye lonke ulwelo olugcwele ipepile esiswini sakho (olunceda ukuthintela ukulibaziseka kwesisu okanye "i-capsaicin cramps").
• Qaphela i-vocal cord spasm (Laryngospasm): Ukuba umntu usezela umgubo wepepile yesiporho okanye uminxe ngelixa eginya ioli yetshilisi eshushu, ukuchaphaza ngequbuliso kwecapsaicin kwilarynx kunokubangela laryngospasm okwethutyana, apho imithambo yelizwi ivaleka ngokukhawuleza imizuzwana engama-20 ukuya kuma-60. Yalela umntu ukuba ahlale ezolile, hlala nkqo, ujongise isilevu sakhe phambili kancinci, kwaye uthathe kancinci, uphefumle ngeempumlo zabo ("ukusezela intyatyambo") kunokuba uphefumle ngamandla ngomlomo wabo, emva koko uphefumlele ngaphandle ngemilebe ekhutshiweyo kude kuphumle iintambo zezwi.

Uthintelo: ukhuseleko lwasekhitshini xa uphethe itshilisi ezishushu¶

Ukuphelisa ukutshisa kwesandla sikaHunan kunye neliso ngokupheleleyo ngokunyanga itshilisi ezishushu njenge-lipid reagent yelabhoratri:

• Nxiba iiglavu zenitrile ezilahlwayo (kungekhona ivinyl okanye ilatex ebhityileyo): Imingxuma emincinci kwirabha yendalo yerabha kunye nevinyl yenkonzo yokutya ekhululekileyo ivumela iimolekyuli ezincinci zecapsaicin ukuba zingene eluswini lwakho kwimizuzu eli-10 ukuya kweli-15 xa uphethe i-habaneros okanye iipepile ezishushu kakhulu. Soloko unxibe i-snug nitrile iimviwo okanye iiglavu zasekhitshini, kwaye uzikhulule ngaphakathi-ngaphandle phambi kokuba uchukumise iiglasi zakho, ifowuni, okanye iziphatho zetephu.
• Faka i-oyile ngezandla zakho phambi kokuba uzinqumle ukuba awunazo iiglavu: Ukuba kufuneka unqunqe iipepile ezishushu ngaphandle kweeglavu, hlikihla ifilimu encinane yeoli yomnquma okanye ioli yemifuno kwizandla ezomileyo phambi kokuba uchukumise iipepile. Oku kugcwalisa kwangaphambili imingxunya yolusu lwakho ngeoyile yokupheka ecocekileyo ukuze i-capsaicin ingakwazi ukungena nzulu, yenza ukucoca isepha emva koko kube lula kakhulu.
• Ungaze ugcaje, ugqobhoze, okanye udibanise iipepile ezishushu kakhulu ekhitshini elingavulwanga umoya: Ukulahla ihabanero okanye ipepile yesiporho kwindawo eyomileyo etshisayo okanye udibanise kwiprosesa yokutya enesantya esiphezulu enolwelo olushushu olukhupha icapsaicin emoyeni, ujike ikhitshi lakho libe ligumbi elimdaka elibangela ukurhawuka kwamehlo kunye ne-vioga yendlu. (ingakumbi iintsana, izilwanyana zasekhaya, kunye nabantu abanesifo sombefu). Vula ihood yoluhlu lwangaphandle kwindawo ephezulu, evulekileyo yeefestile, kwaye uvumele iisosi ezishushu ezixutyiweyo zipholile ngaphambi kokuba uphakamise isiciko se-blender.
• Hlamba iimela kunye neebhodi zokusika ngesepha yesitya kunye namanzi apholileyo: Ukuhlamba ibhodi yokusika egqunywe ngetshilisi ngamanzi ashushu ashushu kubulala i-capsaicin kanye ebusweni bakho. Hlahla ibhodi kunye nemela kuqala ngesepha yokusika igrisi kunye namanzi apholileyo phambi kokuba uzibeke kwisitya sokuhlamba izitya.

Imibuzo edla ngokubuzwa¶

Imithombo ijongiwe¶

• Ukulawulwa kwePoison / Amaziko e-Poison aseMelika (eUnited States): * I-Capsaicin kunye ne-Hot Pepper Exposure Triage: Ukuchithwa kweDermal ("i-Hunan Hand"), i-Ocular Irrigation, kunye neziKhokelo zoNcedo loMlomo *.
• I-American Academy ye-Ophthalmology (AAO, eUnited States): * Ulawulo olungxamisekileyo lwe-Ocular Chemical kunye ne-Oleoresin Capsicum (I-Pepper Spray / i-Chili Oil) Ukubonakaliswa *.
• Iziko leSizwe loKhuseleko lwezeMisebenzi kunye neMpilo / amaZiko oLawulo lweZifo kunye noThintelo (NIOSH / CDC, eUnited States): *Uqhagamshelwano loQhagamshelwano loMsebenzi weDermatitis kunye ne-Mucous Membrane Irritation evela kwiCapsaicinoids *.
• INkonzo yezeMpilo yeSizwe (i-NHS, i-United Kingdom): *Ii-Chemical Eye Burns kunye ne-Acute Skin Irritation First Aid Protocols *.
• UCaterina, M. J., Schumacher, M. A., Tominaga, M., et al. (IYunivesithi yaseKhalifoniya, eSan Francisco / Indalo, eUnited States): I-Capsaicin Receptor: I-Ion Channel ye-Heat-Activated (TRPV1) kwiPay Pathway.

Izikhokelo ezinxulumeneyo¶

• Ukwenzakala kwamehlo
• Ukutshisa
• Ukutshisa okukhulu kunye nokugungxulwa kweekhemikhali
• Ukwalana